Warning

THIS IS NOT THE OFFICIAL GA4GH VRS DOCUMENTATION! This is a demonstration build for discussing advancements to the maturity model and versioning system for GKS specification development. Please refer to https://vrs.ga4gh.org for the GA4GH VRS standard.

Implementation Guide

This section describes the data and algorithmic components that are REQUIRED for implementations of VRS.

• Required External Data: All implementations will require access to sequences and sequence accessions. The Required External Data section provides guidance on the abstract functionality that is required in order to implement VRS.

• Normalization: Expands Alleles to the maximal region of representational ambiguity.

• Computed Identifiers: Generate globally unique identifiers based solely on the variation definition.